Biotin-TRAIL

TRAIL (TNF-related apoptosis-inducing ligand) is a cytokine that is produced and secreted by most normal tissue cells. TRAIL binds to cell surface death receptors DR4 and DR5, by which it activates caspase-8 to induce apoptosis of cancer cells but not of normal cells. This product is made by reacting His6-TRAIL (catalog # U1100) with sulfo-NHS-LC-biotin with a space arm of 22.4 angstrom. It can be used for pulling down TRAIL-interacting proteins by using streptavidin resin.

Additional Information

Product Name: Biotin-TRAIL
Also Known As: TNFSF10; TL2; APO2L; CD253; Apo-2L
Catalog No.: U1110
Size: 20 µg
Molecular Weight: 32.5 kDa
Species: Human
Source: Bacterial recombinant
Stock: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~ 85% by SDS-PAGE
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF Datasheet
NCBI RefSeq: NM_003810.3
Image(s): (Click image to enlarge)

Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified Biotin-TRAIL
Shipping Method: Dry ice shipping
References: N/A

Details

TRAIL (TNF-related apoptosis-inducing ligand) is a cytokine that is produced and secreted by most normal tissue cells. TRAIL binds to cell surface death receptors DR4 and DR5, by which it activates caspase-8 to induce apoptosis of cancer cells but not of normal cells. This product is made by reacting His6-TRAIL (catalog # U1100) with sulfo-NHS-LC-biotin with a space arm of 22.4 angstrom. It can be used for pulling down TRAIL-interacting proteins by using streptavidin resin.

Images:
(Click image to enlarge)

Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified Biotin-TRAIL